Can Opioid Cause Brain Lesions?

A MyOpioidRecoveryTeam Visitor asked a question 💭
December 20, 2025
myOpioidRecoveryTeam

Can opioids cause brain lesions?

The search results provided don't specifically mention brain lesions as a direct effect of opioid use. However, opioids do cause significant changes to brain structure and function over time.

Long-term opioid use reshapes how the brain works, particularly affecting the prefrontal cortex Show Full Answer

Can opioids cause brain lesions?

The search results provided don't specifically mention brain lesions as a direct effect of opioid use. However, opioids do cause significant changes to brain structure and function over time.

Long-term opioid use reshapes how the brain works, particularly affecting the prefrontal cortex (the part responsible for decision-making, judgment, and self-control). This area becomes less active with repeated opioid exposure, weakening its ability to regulate other brain regions like the reward system.

The most serious brain-related danger from opioids is respiratory depression during overdose. When breathing becomes too shallow, oxygen levels can drop dangerously low, potentially causing the heart and brain to shut down. This lack of oxygen could lead to brain damage.

While the brain changes from opioid use are real, they're not necessarily permanent. With treatment, support, and time, the brain can begin to heal and form healthier connections again.

If you're concerned about specific brain changes or lesions, it's important to discuss this with a healthcare provider who can evaluate your individual situation and order appropriate testing if needed.

December 20, 2025
All updates must be accompanied by text or a picture.

Related content

View All

Can And Overdose Cause Brain Lesions On Both Sides Of The Brain?

A MyOpioidRecoveryTeam Visitor asked a question 💭

Has Sublocade Been Known To Cause Brain Lesions?

A MyOpioidRecoveryTeam Visitor asked a question 💭

Is Methamphetamines Considered An Opioid???

A MyOpioidRecoveryTeam Visitor asked a question 💭